For example, the MCV will be low with sideroblastic anemia, but iron stores may be very high. Iron tests: Serum iron, iron-binding capacity, and serum ferritin can be helpful, especially with a low MCV.This test shows variations in cell size, shape, or color. Blood differential: A blood differential may give further clues about anemia.A normal or low reticulocyte count suggests that the body cannot keep up with making new red cells, which may happen when someone is deficient in iron or folate. Reticulocyte count: This measures new red blood cells and is used to determine the cause of anemia.